Clinical trials are a core component of TRENNDZ’s mission to translate research into better neurological care. We participate in and lead trials that evaluate new and existing interventions in real-world Zambian settings, with a strong emphasis on safety, feasibility, and patient outcomes.

Our Approach to Trials

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TRENNDZ trials are designed to:

  • Address questions that are directly relevant to patients seen in our clinics and hospitals
  • Follow rigorous ethical and regulatory standards
  • Involve multidisciplinary teams, including neurologists, pediatricians, nurses, and research staff
  • Build local capacity in trial design, conduct, and analysis

The Neurology Research Office (NRO) provides centralized support for:

  • Protocol development and review
  • Ethics and regulatory submissions
  • Trial start-up and site coordination
  • Participant recruitment and follow-up
  • Data collection, monitoring, and reporting

Active Trials

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Our active trials focus on priority neurological conditions in Zambia. For each trial, we track the study type, participating sites, and enrollment status. Details on individual trials can be obtained by contacting the Neurology Research Office (NRO) or speaking with your clinician.

Completed Trials

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Completed TRENNDZ trials inform clinical practice, guidelines, and future research directions. Summaries of key findings and links to resulting publications are available on our Publications page.

Information for Participants

A clinician speaking with a patient and handing over a consent information leaflet, with icons representing rights, voluntary participation, and privacy.

Participation in clinical research is always voluntary. Before joining any study, potential participants receive detailed information about the purpose of the trial, what participation involves, possible risks and benefits, and their rights as participants.

If you are interested in learning more about ongoing neurology trials, please speak with your clinician or contact the Neurology Research Office (NRO) using the details on our Contact page.